| 摘要 |
<p>This invention provides a immunochromatography detection device that can detect PBP2' produced specifically by a bacterium of multidrug-resistant staphylococcus with high sensitivity in a simple and rapid manner via immunochromatography detection to determine infection with multidrug-resistant staphylococcus, a diagnostic method using such detection device, and a diagnostic kit comprising such detection device. The immunochromatography detection device for detecting multidrug-resistant staphylococcus, which comprises on a sheet-like solid-phase support: a sample supply site on which a sample solution deduced to contain a bacterium producing a cell-wall-synthesizing enzyme, PBP2' or a solution deduced to contain PBP2' released from the cell wall via sample pretreatment is supplied; a labeled reagent site that holds a reagent, which is a labeled antibody binding specifically to PBP2', in a manner such that the reagent is able to spread across the solid-phase support; and a capture reagent site on which a capture reagent capable of specifically binding to and capturing a complex of PBP2' and the labeled reagent has been immobilized, the solid-phase support comprising at the capture reagent site or a site upstream thereof an ampholytic surfactant, an anionic surfactant, and/or a nonionic surfactant.</p> |
