| 摘要 |
<p>The present invention provides methods for treating cancer in humans and other mammals comprising administering a chemotherapeutic agent, such as an interferon, and an aryl urea compound of Formula (I) :
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ B-NH-C(O)-NH-L-M-L 1 -(Q) 1-3 €ƒ€ƒ€ƒ€ƒ€ƒ(I). In Formula (I), B and L and are each, independently, optionally substituted phenyl, naphthyl, a 5 or 6 membered monocyclic heteroaryl group, or an 8 to 10 membered bicyclic heteroaryl group;
M is a bridging group.
each Q is independently C(O)R 4 , C(O)OR 4 and C(O)NR 4 R 5 ; and L' is optionally substituted phenyl, naphthyl, monocyclic heteroaryl or bicyclic heteroaryl, or a saturated or partially saturated, monocyclic or bicyclic carbocyclic moiety or heterocyclic moiety.</p> |
