| 摘要 |
Apparatus and method for the detection of molecular interactions between a plurality of n different molecular species Si(a) (1 </= a </= n) and a further plurality of m molecular species Sg(b) (1 </= b </= m), wherein the Si(a) are immobilized at a phase boundary, and wherein the Sg(b) are comprised in a non-solid phase, in which they are free to move, further comprising: a) a plurality of n + x measuring points Mi(c, a) (1 </= c </= n+x), x comprising the plurality of molecular species Ki(x) (0 </= x </= n) of defined properties, serving as control and/or calibration, located at the phase boundary, onto which measuring points the Si(a) have been immobilized in such a manner that to each measuring point molecules of substantially one molecular species Si(a) are immobilized, and that preferably this set of immobilized molecular species are different at the largest part of the measuring points, and b) a detection system, which is capable of measuring a physical property of a phase boundary at a point Mi(c, a) of the phase boundary, which physical property changes with the advent of an interaction between a molecular species Si(a) and/or Ki(x) immobilized at Mi(c, a) and at least one other molecular species Sg(b), for each measuring point Mi(c, a) independently. |
