METHOD FOR THE ASSESSMENT OF THE INHIBITORY ACTIVITY OF ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR
摘要
<p>A method for the assessment of the inhibitory activity of an antibody for inhibiting the binding of IGF-1 and/or IGF-2 to IGF-1R in a lysed PBL sample of a mammal which has been treated with said antibody, characterized in that the IGF-1R protein level of said PBLs is measured as a measure for the inhibitory activity of said antibody.</p>
申请公布号
WO2008104344(A1)
申请公布日期
2008.09.04
申请号
WO2008EP01457
申请日期
2008.02.25
申请人
F. HOFFMANN-LA ROCHE AG;EVERS, STEFAN;HINZ, ANDREAS;KUENKELE, KLAUS-PETER