发明名称 Macrocylic Inhibitors Of Hepatitis C Virus
摘要 Inhibitors of HCV of formula (I). and the N-oxides, salts, and stereoisomers thereof, wherein the dashed line represents an optional double bond between atoms C7 and C8; R<SUP>1 </SUP>is hydrogen or C<SUB>1-6</SUB>alkyl; R<SUP>2 </SUP>is hydrogen or C<SUB>1-6</SUB>alkyl; and n is 3, 4, 5, or 6; pharmaceutical compositions containing compounds (I) and processes for preparing compounds (I) are provided. Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.
申请公布号 US2008200503(A1) 申请公布日期 2008.08.21
申请号 US20060995888 申请日期 2006.07.28
申请人 发明人 SIMMEN KENNETH ALAN;DE KOCK HERMAN AUGUSTINUS;RABOISSON PIERRE JEAN-MARIE BERNARD;LINDSTROM MATS STEFAN;KAHNBERG PIA CECILIA;ANTONOV DMITRY;NILSSON KARL MAGNUS;SAMUELSSON BENGT BERTIL;ROSENQUIST ASA ANNICA KRISTINA
分类号 A61K31/4709;C07D401/14 主分类号 A61K31/4709
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