The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analysing a library of template polynucleotides suitable for methylation analysis.
申请公布号
WO2008096146(A1)
申请公布日期
2008.08.14
申请号
WO2008GB00431
申请日期
2008.02.06
申请人
SOLEXA LIMITED;THE BROAD INSTITUTE OF MIT;GORMLEY, NIALL;GNIRKE, ANDREAS;JAFFE, DAVID;NUSBAUM, HARRIS