COMPOUNDS HAVING ANTI-ADHESIVE EFFECTS ON CANCER CELLS
摘要
<p>Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3 '- > P5' thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least one G-rich sequence motif as described, are effective to morphologically alter and reduce adhesion of cancer cells.</p>
申请公布号
WO2008094640(A2)
申请公布日期
2008.08.07
申请号
WO2008US01277
申请日期
2008.01.30
申请人
GERON CORPORATION;UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER;GRYAZNOV, SERGEI, M.;SHAY, JERRY, W.;WRIGHT, WOODRING
