发明名称 |
Pimecrolimus Foam Composition Containing Hexylene Glycol, Optionally Oleyl Alcohol, Dimethylisosorbide and/or Medium Chain Triglycerides |
摘要 |
Pharmaceutical foam compositions substantially free of ethanol and comprising pimecrolimus in a carrier vehicle comprising a mixture of oily solvents amounting to at least 40% of the total weight of the composition and consisting of: i) hexylene glycol; ii) optionally oleyl alcohol; and iii) dimethylisosorbide and/or medium chain triglycerides; and additionally: iv) when oleyl alcohol is absent, water in an amount of less than 25%; v) at least one consistency agent; vi) at least one preservative; and vii) at least one surfactant/emulgator; and propellant gas for foaming; and optionally further conventional excipients. They are indicated for use in the treatment of various skin, nail and mucosal diseases.
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申请公布号 |
US2008181854(A1) |
申请公布日期 |
2008.07.31 |
申请号 |
US20050547226 |
申请日期 |
2005.04.07 |
申请人 |
NOVARTIS AG |
发明人 |
EINI MEIR;FRIEDMAN DORON;HIRSCH STEFAN;MEYENBURG SABINE;SEKKAT NABILA;TAMARKIN DOV |
分类号 |
A61K9/12;A61K9/00;A61K31/445;A61K47/10;A61K47/14;A61K47/26;A61P29/00 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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