Aqueous ophthalmic solutions containing a combination of hyaluronic acid or a pharmaceutically acceptable salt thereof, e.g. sodium hyaluronate, and polyvinyl alcohol are disclosed. These solutions have a synergistic effect on viscosity and provide a statistically significant improvement over the prior art formulations. The solutions are used as artificial tear for the treatment of dry eye syndrome and ocular discomfort and may be administered whenever the use of artificial tears is advisable. The solutions are also suitable for use as vehicle for ophthalmic drugs.
申请公布号
WO2008011836(A3)
申请公布日期
2008.07.31
申请号
WO2007CR00001
申请日期
2007.07.24
申请人
OSMOTICA COSTA RICA, SOCIEDAD ANONIMA;FAOUR, JOAQUINA;PASTINI, ANA C.