发明名称 |
METHOD FOR THE EVOLUTIONARY DESIGN OF BIOCHEMICAL REACTION NETWORKS |
摘要 |
The present invention relates to methods for achieving an optimal function of a biochemical reaction network. The methods can be performed in silico using a reconstruction of a biochemical reaction network of a cell and iterative optimization procedures. The methods can further include laboratory culturing steps to confirm and possibly expand the determinations made using the in silico methods, and to produce a cultured cell, or population of cells, with optimal functions. The current invention includes computer systems and computer products including computer-readable program code for performing the in silico steps of the invention.
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申请公布号 |
US2008176327(A1) |
申请公布日期 |
2008.07.24 |
申请号 |
US20070927254 |
申请日期 |
2007.10.29 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
PALSSON BERNHARD O.;EDWARDS JEREMY S. |
分类号 |
C12N5/02;C12N15/09;C12N1/14;C12N1/15;C12N1/16;C12N1/19;C12N1/20;C12N1/21;C12N5/10;G06F17/30;G06F19/00 |
主分类号 |
C12N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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