| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention describes prednisolone metasulfobenzoate composition of controlled released within large intestine, containing sodium prednisolone metasulfobenzoate, hyaloid amylase coated, ethylcellulose and dibutyl-sebacate with ratio amylase to ethylcellulose 1:3.5 to 1:4.5, and amylase is wheat or corn amylase. Method of composition making is provided as well. ^ EFFECT: directed released of sodium prednisolone metasulfobenzoate in large intestine at low systemic action and no systemic by-effects. ^ 12 cl, 2 dwg, 6 ex |
