<p>Compositions and methods for identifying modulators of sortilin are described. The methods are particularly useful for identifying analytes that antagonize sortilin s effect on processing of amyloid precursor protein to Aß peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease.</p>
申请公布号
WO2008076262(A2)
申请公布日期
2008.06.26
申请号
WO2007US25331
申请日期
2007.12.11
申请人
MERCK & CO., INC.;GETTY, KRISTA, L.;RAY, WILLIAM, J.;PAWELETZ, CLOUD, P.
发明人
GETTY, KRISTA, L.;RAY, WILLIAM, J.;PAWELETZ, CLOUD, P.