发明名称 CONTROLLED RELEASE DOSAGE FORMS OF ZOLPIDEM
摘要 <p>A controlled release dosage forms comprising zolpidem or a salt thereof to release zolpidem to induce rapid onset of sleep, and continue to release zolpidem in a controlled manner to maintain effective plasma concentrations over an extended period of time to improve sleep maintenance. The pharmaceutical controlled-release dosage form of zolpidem or a salt thereof having a dissolution profile when measured in a type I or II dissolution apparatus according to the U.S. Pharmacopoeia in 0.01M hydrochloric acid buffer at 37° C., such that less than 40 % is released at the end of 30 minutes.</p>
申请公布号 WO2008075372(A1) 申请公布日期 2008.06.26
申请号 WO2007IN00046 申请日期 2007.02.07
申请人 LUPIN LIMITED;BHANDARI, NILESH;RAGHAVAN, VINEETH;JAYANTHI, SURYA, KUMAR;SEN, HIMADRI 发明人 BHANDARI, NILESH;RAGHAVAN, VINEETH;JAYANTHI, SURYA, KUMAR;SEN, HIMADRI
分类号 A61K31/437;A61K9/16;A61K9/20;A61K9/28;A61P25/20 主分类号 A61K31/437
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