发明名称 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF (-)-HALOFENATE AND INTERMEDIATES THEREOF
摘要 The present invention provides a compounds the formula (IV): and methods for producing an alpha-(phenoxy)phenylacetic acid compound of the formula: wherein R1 is a member selected from the group consisting of: each R2 is a member independently selected from the group consisting of (C1-C4)alkyl, halo, (C1-C4)haloalkyl, amino, (C1-C4 aminoalkyl, amido, (C1-C4)amidoalkyl, (C1-C4)sulfonylalkyl, (C1-C4)sulfamylalkyl, (C1-C4)allcoxy, (C1-C4)heteroalkyl, carboxy and nitro; the subscript n is 1 when R1 has the formula (a) or (b) and 2 when R1 has the formula (c) or (d); the subscript m is an integer of from O to 3; * indicates a carbon which is enriched in one stereoisomeric configuration; and the wavy line indicates the point of attachment of R1; and compounds.
申请公布号 KR20080050527(A) 申请公布日期 2008.06.05
申请号 KR20087009709 申请日期 2006.09.21
申请人 METABOLEX, INC. 发明人 ZHU YAN;CHENG PENG;CHEN XIN;MA JINGYUAN;ZHAO ZUCHUN
分类号 C07D207/06;C07D241/04;C07D265/30 主分类号 C07D207/06
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