发明名称 NEW PYRIDYLETHANOLAMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION
摘要 Pyridylethanolamines of the formula <IMAGE> in which R denotes a carboxymethoxy, carbomethoxymethoxy, ethoxycarbonylmethoxy or 2-hydroxyethoxy group, their optical isomers, their diastereomers and their acid addition salts. The novel compounds of the above formula I, their optical isomers and their diastereomers and also their acid addition salts, in particular their physiologically tolerable acid addition salts with inorganic or organic acids, have useful pharmacological properties, namely an effect on the metabolism, preferably a hypoglycaemic and body fat-reducing effect, and also a lowering effect on the atherogenic beta -lipoproteins VLDL and LDL. The novel compounds of the above formula I can be prepared by processes which are known per se.
申请公布号 ZA8806501(B) 申请公布日期 2008.05.30
申请号 ZA19880006501 申请日期 1988.09.01
申请人 DR KARL THOMAE GMBH 发明人 MAFRED REIFFEN;WOLFGAN GRELL;ECKHARD RUPPRECHT;MICHAEL MARK;ROBERT SAUTER;RUDOLF HURNAUS
分类号 A61K31/44;C07D;A23K;A61K;A61K31/4402;A61K31/4418;A61P3/06;A61P3/08;A61P3/10;A61P9/10;C07D213/36;C07D213/38;C07D213/61;C07D277/28;C07D277/32 主分类号 A61K31/44
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