发明名称 |
Diagnos and Treatment of Fibrosis Related Pathology |
摘要 |
This application is directed to a method for the treatment of fibrosis, preferably liver fibrosis, pulmonary fibrosis and cardiac fibrosis, in a subject in need of such treatment comprising administering to said subject an amount of an inhibitor of HNOEL-iso polypeptide sufficient to effect a substantial inhibition of the HNOEL-iso polypeptide so as to thereby treat the subject. This application is also directed to a process of obtaining a compound which inhibits human HNOEL-iso polypeptide. This application is also directed to use of a compound identified by that process in the preparation of a medicament for therapy of disease, in particular fibrosis, and to diagnostic aspects related to HNOEL-iso polypeptide.
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申请公布号 |
US2008124317(A1) |
申请公布日期 |
2008.05.29 |
申请号 |
US20040562177 |
申请日期 |
2004.06.24 |
申请人 |
MOR ORNA;FAERMAN ALEXANDER;FEINSTEIN ELENA |
发明人 |
MOR ORNA;FAERMAN ALEXANDER;FEINSTEIN ELENA |
分类号 |
A61K39/395;A61B;A61K31/7105;A61P19/02;A61P19/10;C07K14/47;C07K16/18;G01N33/576 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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