| 摘要 |
This invention describes a method to analyze chromosomal abnormalities in a single cell or a few cells for preimplantation genetic research and diagnosis. The method also applies to other applications using single cells such as stem cell and transformed cell research and diagnosis and cancer diagnosis. The invention uses genome amplification along with genome labeling and/or specific gene labeling techniques. The amplified genetic material is detected on microarray platforms in various formats. The invention features multiplexing assays and detection of multiple types of chromosomal abnormalities.
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