发明名称 |
DIRECT DRUG DELIVERY SYSTEM BASED ON THERMALLY RESPONSIVE BIOPOLYMERS |
摘要 |
A method for delivering a drug depot of a compound of interest to a selected region in a subject. The method comprises administering a composition directly to said region of interest, the composition comprising the compound of interest to be delivered (such as an antiinflammatory agent or a chemotherapeutic agent) and a polymer (such as an elastin-like peptide or ELP) that undergoes an inverse temperature phase transition, so that a sustained release of the compound of interest at the selected region is provided. Compositions useful for carrying out the invention are also described. |
申请公布号 |
KR20080045118(A) |
申请公布日期 |
2008.05.22 |
申请号 |
KR20087001872 |
申请日期 |
2006.06.21 |
申请人 |
DUKE UNIVERSITY |
发明人 |
SETTON LORI A.;CHILKOTI ASHUTOSH;KRAUS VIRGINIA B.;BETRE HELAWE;DREHER MATTHEW R. |
分类号 |
A61K9/14;A61K39/395;A61M31/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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