| 摘要 |
<p>According to the present invention, there is provided a noninvasive method for rapid detection of biomarkers, including the steps of subjecting biological material to laser beam irradiation of a single wavelength, enhancing the scattered light returned from passage of said excitation light through the biological material, transmitting this scattered light and measuring it, to obtain data which is characteristic of the biological material being tested, comparing the spectral data to reference spectral data obtained from laser irradiation of the same wavelength applied to a known biological sample contaminated with the biomarker being detected, receiving a diagnosis of the presence or absence of biomarkers of the disease in the biological material, and determining the quantitative value of the biomarkers in the biological material. Also provided is a diagnostic tool for detecting the presence of a biomarker in a sample, the tool including a laser beam irradiation device with excitation light of a certain wavelength, an enhancing kit for enhancing the scattered light returned from passage of the excitation light, through the biological material, and a measurement device to obtain data which is characteristic of the biological material being tested, a comparing device for comparing the data to reference spectral data obtained from laser irradiation of the same wavelength applied to a known biological sample that has the biomarker, a quantitator for quantitating the value of the biomarker in the biological material and a display device for displaying the diagnosis.</p> |
