发明名称 |
Adenovirus vectors for gene therapy |
摘要 |
The present invention relates to novel adenovirus vectors for use in gene therapy which are designed to prevent the generation of replication-competent adenovirus (RCA) during in vitro propagation and clinical use. The invention also provides methods for the production of the novel virus vectors. These vectors maximize safety for clinical applications in which adenovirus vectors are used to transfer genes into recipient cells for gene therapy.
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申请公布号 |
EP1923467(A2) |
申请公布日期 |
2008.05.21 |
申请号 |
EP20080101446 |
申请日期 |
1996.03.20 |
申请人 |
GENZYME CORPORATION |
发明人 |
ARMENTANO, DONNA;ROMANCZUK, HELEN;WADSWORTH, SAMUEL C. |
分类号 |
C12N15/09;C12N15/861;A61K35/76;A61K48/00;C07K14/47;C12N15/00;C12N15/12;C12R1/92 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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