PERCUTANEOUSLY ABSORBABLE OPHTHALMIC PREPARATION

摘要

The present invention provides a percutaneously absorbable ophthalmic preparation that permits the retention of a therapeutically effective concentration of a heterocyclic spiro compound and a salt thereof for promoting lacrimation, and that produces less adverse reactions such as miosis. Specifically, the present invention provides a percutaneously absorbable ophthalmic preparation comprising as an active ingredient a heterocyclic spiro compound represented by the general formula (I):
[wherein the symbols have the same definitions as those given in the description] or a pharmaceutically acceptable salt thereof.