发明名称 Companion diagnostic assays for endothelin receptor antagonists
摘要 Methods for identifying cancer patients eligible to receive endothelin receptor antagonist therapy and for monitoring patient response to endothelin receptor antagonist therapy comprise assessment of the expression levels of at least one of PAI-1, uPA, TGFbeta2, IL-6, IL-8 and OPG in a patient tissue sample. The methods of the invention allow more effective identification of patients to receive endothelin receptor antagonist therapy and of determination of patient response to the therapy.
申请公布号 US2008102451(A1) 申请公布日期 2008.05.01
申请号 US20060590007 申请日期 2006.10.31
申请人 ABBOTT LABORATORIES 发明人 LESNIEWSKI RICHARD R.;SEMIZAROV DIMITRI;VAN SANT CHARLES L.
分类号 G01N33/50;C12Q1/68;G01N33/52;G01N33/53;G01N33/543 主分类号 G01N33/50
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