发明名称 |
SCREENING METHOD FOR GPCR LIGANDS |
摘要 |
This invention relates to a method of identifying a compound capable of binding to a target domain of a G-protein coupled receptor comprising the steps of: (a) providing a receptor comprising said target domain and a first group linked to said target domain; (b) bringing into contact said receptor of (a) with a test molecule comprising a second group and said compound linked to each other, wherein said first group binds said second group; and (c) determining, subsequent to the binding of said first group to said second group, whether said compound binds to said target domain. |
申请公布号 |
WO2008022716(A3) |
申请公布日期 |
2008.04.10 |
申请号 |
WO2007EP07071 |
申请日期 |
2007.08.09 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.;HAUSCH, FELIX;PEREZ-BALDERAS, FRANCISCO |
发明人 |
HAUSCH, FELIX;PEREZ-BALDERAS, FRANCISCO |
分类号 |
C07K14/575;C07K14/585;G01N33/566;G01N33/68 |
主分类号 |
C07K14/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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