PROCESS FOR THE PREPARATION OF MEMANTINE AND ITS HYDROCHLORIC ACID SALT FORM
摘要
The present invention relates to the synthesis of 1-amino-3,5-dimethyladamantane ("memantine") and its hydrochloric acid salt form. In particular a new intermediate (N-chloro-acetylamino-3,5-dimethyladamantane) for the synthesis of memantine as well as a new process for the preparation of memantine and its hydrochloric acid salt form using said intermediate is disclosed.
申请公布号
WO2008040560(A1)
申请公布日期
2008.04.10
申请号
WO2007EP08684
申请日期
2007.10.05
申请人
KRKA, D.D., NOVO MESTO;TIHI, JAROSLAV;MELEH, MARIJA;VRECER, FRANC;ZUPET, ROK;PUCELJ, JOZE;PELKO, MITJA
