发明名称 CARBAPENEM FOR ORAL ADMINISTRATION
摘要 PROBLEM TO BE SOLVED: To provide a carbapenem antibiotic substance having strong antibacterial power, wide antibacterial spectrum and excellent oral absorbability. SOLUTION: The antibacterial agent contains a compound of formula (I) or its pharmacologically permissible salt. In the formula, R<SP>1</SP>and R<SP>2</SP>are each independently a hydrogen atom or a 1-6C alkyl; R<SP>3</SP>and R<SP>4</SP>are each independently a hydrogen atom or a 1-6C alkyl or R<SP>3</SP>and R<SP>4</SP>together form a (substituted) heterocyclic group together with adjacent nitrogen atom; R<SP>5</SP>is a hydrogen atom or a metal ion such as potassium or sodium ion; and X is a leaving group such as Cl, Br, I and -OSO<SB>2</SB>CF<SB>3</SB>. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008074803(A) 申请公布日期 2008.04.03
申请号 JP20060258291 申请日期 2006.09.25
申请人 MEIJI SEIKA KAISHA LTD 发明人 AIHARA KAZUHIRO;SAWABE TAKEHIKO;AOKI MAKOTO
分类号 C07D477/00;A61K31/427;A61K31/454;A61P31/04;A61P43/00;C07D487/04 主分类号 C07D477/00
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