发明名称 |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules |
摘要 |
Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.
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申请公布号 |
US2008075672(A1) |
申请公布日期 |
2008.03.27 |
申请号 |
US20070703610 |
申请日期 |
2007.02.06 |
申请人 |
GANTIER RENE;VEGA MANUEL;DRITTANTI LILA;GUYON THIERRY |
发明人 |
GANTIER RENE;VEGA MANUEL;DRITTANTI LILA;GUYON THIERRY |
分类号 |
C07K14/535;A61K9/12;A61K31/7088;A61K38/00;A61K38/19;C07K14/475;C07K14/505;C07K14/52;C07K14/53;C07K14/54;C07K14/555;C07K14/575;C07K14/61;C12N1/00;C12N15/19;C12N15/20;C12N15/24;C12N15/27;C12N15/63;C12P21/02;C40B40/06 |
主分类号 |
C07K14/535 |
代理机构 |
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代理人 |
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地址 |
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