PROCESS FOR PREPARATION OF DIPHENYLPHOSPHATE SALT OF DI(2-CHLOROETHYL)AMINE

摘要

The process for preparation of diphenylphosphate salt of di(2-chloroethyl)amine of the formula:comprises the reaction between diphenylphosphate and di(2-chloroethyl)amine. The synthesis is implemented in one stage without the isolation of intermediates at the interaction between hydrochloric salt of di(2-chloroethane)amine, diphenylphosphate chloroanhydride and triethylamine in aquatic environment at the temperature no higher than 13°С, with subsequent isolation of crystal product from the reaction mixture by filtration and purification.