摘要 |
<p>The present application is directed to a method for the purification of Radium, in particular <SUP>226</SUP>Ra1 for target preparation for an essentially pure <SUP>225</SUP>Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is further related to a method for recycling of <SUP>226</SUP>Ra, for target preparation for <SUP>225</SUP>Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced <SUP>225</SUP>Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained <SUP>226</SUP>Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li1 Mg1 Mn, Na1 Ni1 Pb1 Sr1 V, Zn, and Ba.</p> |
申请人 |
ACTINIUM PHARMACEUTICALS, INC.;KABAI, EVA;MORENO BERMUDEZ, JOSUE, MANUEL;HENKELMANN, RICHARD;TUERLER, ANDREAS |
发明人 |
KABAI, EVA;MORENO BERMUDEZ, JOSUE, MANUEL;HENKELMANN, RICHARD;TUERLER, ANDREAS |