ATTENUATED MUTANT ORIGINATED FROM AVIAN ESCHERICHIA COLI, VACCINE FOR AVIAN ESCHERICHIA COLI COUNTERMEASURE, IMMUNIZATION METHOD AND VACCINE VECTOR FOR CHICKEN

摘要

PROBLEM TO BE SOLVED: To provide a safe and effective attenuated live vaccine strain which can also be applied to broiler commercial chickens by a simple administration method except injection against avian Escherichia coli symptoms causing large economical damages.

SOLUTION: An avian Escherichia coli-originated attenuated mutant AESN 1331 which is a serum type 078 strain most high frequently separated, originated from avian Escherichia coli, does not have the possibility of reverse mutation, and is deposited as an accession number: FERM P-20986, and in which the function of a gene encoding cyclic AMP receptor protein (crp) is inactivated.

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