| 发明名称 |
ANTI-GFRALPHA3 ANTIBODIES |
| 摘要 |
<p>Antibodies and antibody fragments that bind to the receptor GFRalpha3 and inhibit formation of a Neublastin-GFRalpha3-Ret ternary complex are disclosed. Also disclosed are methods of using the antibodies and antibody fragments to inhibit phosphorylation of Ret in a cell and treat disorders and in a subject.</p> |
| 申请公布号 |
EP1896047(A1) |
申请公布日期 |
2008.03.12 |
| 申请号 |
EP20060785113 |
申请日期 |
2006.06.16 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
WORLEY, DANE, S.;SAH, DINAH, WEN-YEE;SEAMANS, KATHERINE, W. |
| 分类号 |
A61K38/00;C07K2/00;C07K4/00;C07K5/00;C07K7/00;C07K14/00;C07K16/00;C07K17/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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