发明名称 Pyridazine derivatives and their use as therapeutic agents
摘要 Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where x, y, W, V, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>6a</SUP>, R<SUP>7</SUP>, R<SUP>7a</SUP>, R<SUP>8</SUP>, R<SUP>8a</SUP>, R<SUP>9 </SUP>and R<SUP>9a </SUP>are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
申请公布号 US7335658(B2) 申请公布日期 2008.02.26
申请号 US20040901563 申请日期 2004.07.29
申请人 XENON PHARMACEUTICALS INC. 发明人 CHAKKA NAGASREE;CHAFEEV MIKHAIL;CHOWDHURY SULTAN;FU JIAN-MIN;HOU DUANJIE;KAMBOJ RAJENDER;KODUMURU VISHNUMURTHY;LIU SHIFENG;RAINA VANDNA;SUN SHAOYI;SVIRIDOV SERGUEI;WINTHER MICHAEL D;ZHANG ZAIHUI;ABREO MELWYN;HOLLADAY MARK W;LI WENBAO;SUN SENGEN;TU CHI;GSCHWEND HEINZ W
分类号 C07D403/04;A61K31/00;A61K31/497;A61K31/501;A61K31/551;A61P3/06;C07D237/20;C07D237/24;C07D403/14 主分类号 C07D403/04
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