发明名称 HETEROARYL-CARBOXYLIC ACID(SULFAMOYL ALKYL)AMIDE-DERIVATIVES AS FACTOR XA INHIBITORS
摘要 The present invention relates to compounds of the Formula (I), in which R1; R2; R3; V; G1 and G2 have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa, and can in general be applied in conditions in which an undesired activity of factor Xa is present or for the cure or prevention of which an inhibition of factor Xa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula (I), their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
申请公布号 KR20080015800(A) 申请公布日期 2008.02.20
申请号 KR20077027048 申请日期 2006.05.06
申请人 SANOFI-AVENTIS 发明人 WAGNER MICHAEL;URMANN MATTHIAS;WEHNER VOLKMAR;LORENZ MARTIN;BAUER ARMIN;NAZARE MARC;MATTER HANS
分类号 C07D409/12;A61K31/4535;A61P7/02 主分类号 C07D409/12
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