发明名称 |
GENERATION OF PHOSPHORUS OXYCHLORIDE AS BY-PRODUCT FROM PHOSPHORUS PENTACHLORIDE AND DMF AND ITS USE FOR CHLORINATION REACTION BY CONVERTING INTO VILSMEIER-HAACK REAGENT. |
摘要 |
<p>A process is described wherein after formation of first crop of Vilsmeier-Haack reagent by reacting Phosphorus Pentachloride with N,N-dimethylformamide to form a first crop of Vilsmeier reagent as insoluble crystals, a by-product of this reaction, the Phosphorus Oxy-Chloride, reacts with N,N-dimethylformamide to give a second crop of Vilsmeier reagent. This second crop of Vilsmeier reagent is soluble in DMF. This process makes it possible to double the yield of chlorinated substrate, such as sucrose-6-acetate or sucrose-6-benzoate, from the same quantity of Phosphorus Pentachloride.</p> |
申请公布号 |
EP1888611(A2) |
申请公布日期 |
2008.02.20 |
申请号 |
EP20060809914 |
申请日期 |
2006.04.28 |
申请人 |
PHARMED MEDICARE PRIVATE LIMITED |
发明人 |
RATNAM, RAKESH;SUNDEEP, AURORA;MOFIZUDDIN, MOHAMMED |
分类号 |
C07H1/00;C07B39/00;C07C249/02;C07H5/00;C07H5/02;C07H13/04;C07H13/08 |
主分类号 |
C07H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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