发明名称 ALPHA-(ARYL-OR HETEROARYL-METHYL)-BETA-PIPERIDINOPROPANOIC ACID COMPOUNDS AS ORL1-RECEPTOR ANTAGONISTS
摘要 This invention provides the compounds of formula (I): or a pharmaceutically acceptable ester or salt thereof, wherein R1 and R2 independently represent hydrogen or the like; R3 represents aryl or the like;-X-Y-represents-CH2O-or the like; and n represents 0, 1 or 2. These compounds have ORL1-receptor antagonist activity; and therefore, are useful to treat diseases or conditions such as pain, various CNS diseases etc.
申请公布号 KR20080012977(A) 申请公布日期 2008.02.12
申请号 KR20077029447 申请日期 2007.12.17
申请人 PFIZER INC. 发明人 HASHIZUME YOSHINOBU;HIROTA MASAKO;KOIKE HIROKI;MATSUMOTO YUKARI;MIHARA SACHIKO;NAKAMURA HIROSHI
分类号 C07D451/06;A61K31/343;C07D491/10 主分类号 C07D451/06
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