发明名称 |
Potentiation of the immune response |
摘要 |
A method for stimulating proliferation of T-cells containing cytoplasmic post-prolyl dipeptidase activity; the method, in one aspect, involves contacting the T-cells with an organic compound at a concentration below 10<SUP>-8</SUP>M, wherein the compound is characterized in that: (a) it is capable of crossing the membrane of T-cells to enter the cytoplasm, (b) it binds to the dipeptidase activity at a concentration of below 10<SUP>-8</SUP>M, and thus (c) stimulates proliferation of the T-cells at that concentration.
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申请公布号 |
US2008026007(A1) |
申请公布日期 |
2008.01.31 |
申请号 |
US20070703058 |
申请日期 |
2007.02.06 |
申请人 |
HUBER BRIGITTE T;SCHMITZ TRACY;UNDERWOOD ROBERT |
发明人 |
HUBER BRIGITTE T.;SCHMITZ TRACY;UNDERWOOD ROBERT |
分类号 |
A61K39/00;A61K45/00;A61K38/55;A61K39/39;A61P31/18;A61P37/04;A61P43/00;C07K14/155;C07K14/73 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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