发明名称 |
Solid oral pharmacological composition containing a derivative of bisphosphonic acid and method of obtaining same |
摘要 |
Solid oral pharmaceutical composition comprising bisphosphonic acid derivative contains the cores based on a carbohydrate alcohol, preferably mannitol, uniformly dispersed in a homogenous blend of an active ingredient and excipients. The process of preparation of the above pharmaceutical formulation is also disclosed. The invention is particularly suitable to prepare solid oral dosage forms of the medicines comprising alendronic acid derivative, especially alendronic acid monosodium salt trihydrate. |
申请公布号 |
PL196485(B1) |
申请公布日期 |
2008.01.31 |
申请号 |
PL20000340087 |
申请日期 |
2000.05.11 |
申请人 |
INSTYTUT FARMACEUTYCZNY |
发明人 |
ADAMSKI STANISLAW;ZAREMBA ANDRZEJ;SZELEJEWSKI WIESLAW;MARCHLEWSKA-CELA HANNA;BERKAN KATARZYNA |
分类号 |
A61K9/20;A61K31/663;A61P19/00 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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