摘要 |
The present invention provides a process for the preparation 6-[3-(hetero)aryloxy-2-fluoro-benzyl]-2H-pyridazin-3-one compounds 1 where R2 is an optionally substituted aryl or an optionally substituted heteroaryl, R<SUP>6 </SUP>is NO<SUB>2</SUB>, NH<SUB>2</SUB>, alkyl, halogen, or a function group readily derived therefrom and R<SUP>4c </SUP>is hydrogen or alkyl. There also is provided a process for the preparation of phenylacetic acid compounds 2, wherein R<SUP>2 </SUP>and R<SUP>6 </SUP>are as defined previously and R<SUP>5a </SUP>is hydrogen or alkyl, which are useful for the preparation of pyridazinone compounds.
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