<p>An isolated IKK2-55 gene and polypeptide; DINO gene and polypeptide; LLR-J24-stalk nucleotide and polypeptide, a polynucleotide encoding the transmembrane protein LLR-J24 and the transmembrane protein LLR-J24; a polynucleotide encoding the extracellular domain of LLR-J24 and a polypeptide which is the extracellular domain of LLR-J24; their use in a method of identifying an agonist or antagonist of such polypeptide/protein; and an antagonist or an agonist of such polypeptide/protein and its use as a pharmaceutical.</p>
申请公布号
EP1881007(A1)
申请公布日期
2008.01.23
申请号
EP20070105229
申请日期
2002.03.26
申请人
NOVARTIS AG;NOVARTIS-PHARMA GMBH
发明人
DE MARTIN, RAINER;SCHMID, JOHANNES;HOFER-WARBINEK, RENATE;HOFER, ERHARD;KALTHOFF, FRANK STEPHAN;LIPP, HANS-JOACHIM;MECHTCHERIAKOVA, DIANA;SOBANOV, YURI