发明名称 |
PROCESS FOR PRODUCING LIGANDS, LIGANDS AND TEST KIT |
摘要 |
<p>The invention relates to a method for producing ligands, in particular aptamers. With this method, a target substance is offered to a set of candidate ligands, and the unbonded ligands are separated out by a cross-flow filtration process. The retentate, which contains ligand-target substance complexes, then undergoes further continuous cross-flow filtration while chemical and/or physical parameters are being varied. After each variation of a parameter, those candidate ligands whose bond with the target substance was dissolved by the parameter variation are collected in separate fractions and separately multiplied.</p> |
申请公布号 |
EP1880017(A1) |
申请公布日期 |
2008.01.23 |
申请号 |
EP20060724612 |
申请日期 |
2006.04.27 |
申请人 |
ANALYTICON BIOTECHNOLOGIES AG |
发明人 |
OBERSTRASS, JUERGEN;MEISEGEIER, BERNHARD;ZWINGMANN, DETLEV |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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