| 发明名称 |
RECOMBINANT TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE WITH IMPROVED FUNCTIONALITY |
| 摘要 |
Truncated terminal deoxynucleotidyl transferase (TdT) derivative from calf thymus characterized in that the derivative in comparison to the native TdT is N- terminally truncated by up to 161 amino acids and has a 20- 30-fold higher enzyme activity in solutions containing Co~ions, and it's recombinant production and use.</SDOA B>
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| 申请公布号 |
CA2423887(C) |
申请公布日期 |
2008.01.22 |
| 申请号 |
CA20032423887 |
申请日期 |
2003.04.01 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
PAJATSCH, MARKUS;MUELLER, RAINER;SOBEK, HARALD;CURDT, INGO;SONN, KIRSTEN;SCHMIDT, MANFRED;SUPPMANN, BERNHARD;SCHNEIDINGER, BERND |
| 分类号 |
C12N9/12;C12N15/09;C12N9/10;C12N15/54;C12N15/63;C12P19/34;C12P21/02;C12Q1/48;G01N33/573 |
主分类号 |
C12N9/12 |
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