发明名称 |
Stable pharmaceutical compositions of 2-aza-bicyclo(3.3.0)-octane-3-carboxylic acid derivatives |
摘要 |
Provided are stable pharmaceutical compositions comprising from about 2.5% to about 20% of a 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivative by weight of the composition and at least one pharmaceutically acceptable excipient, wherein the composition preferably has a total weight of less than 100 mg. Also provided are stable pharmaceutical compositions comprising a 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivative in a stabilizing-effective concentration and at least one pharmaceutically acceptable excipient. Further provided are methods for improving the stability of a pharmaceutical composition and methods for treating hypertension by administering a therapeutically effective amount of the stable pharmaceutical compositions of the invention.
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申请公布号 |
US2008015188(A1) |
申请公布日期 |
2008.01.17 |
申请号 |
US20070788771 |
申请日期 |
2007.04.19 |
申请人 |
HRAKOVSKY JULIA;SEBBAN HAGIT |
发明人 |
HRAKOVSKY JULIA;SEBBAN HAGIT |
分类号 |
A61K31/54;A61K31/535;A61P7/00 |
主分类号 |
A61K31/54 |
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