发明名称 |
GENERATION OF ION-EXCHANGE MEDIA |
摘要 |
The present invention relates to a method of generating a separation medium comprising mixed mode cation-exchanger ligands coupled to a base matrix, which method comprises to provide a scaffold comprising a functional group and exhibiting a cyclic core structure; derivatise the scaffold with a reagent comprising a reactive group coupled to a residue R by reacting the functional group of the scaffold with said reactive group; open the cyclic structure of the resulting derivative; and react the product with a base matrix comprising a reactive group. The scaffold presents at least two functionalities; one sulphur-comprising group for coupling to the base matrix and one group that can be transformed into an ionic group. |
申请公布号 |
EP1425092(B1) |
申请公布日期 |
2008.01.16 |
申请号 |
EP20020798880 |
申请日期 |
2002.09.12 |
申请人 |
GE HEALTHCARE BIO-SCIENCES AB |
发明人 |
MALOISEL, JEAN-LUC;THEVENIN, NICOLAS |
分类号 |
B01J20/22;B01J45/00;B01D15/00;B01J20/32;B01J39/08;B01J39/16;B01J39/18;B01J39/26 |
主分类号 |
B01J20/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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