发明名称 |
ANTIBODY DIRECTED AGAINST GASTRIN-RELEASING PEPTIDE PRECURSOR AND USE THEREOF |
摘要 |
<p>Disclosed is a novel method for determination of ProGRP which is free from problems such as the dispersion in the values of measurements and operational constraints such as handling of a test sample. A method for the determination of a gastrin-releasing peptide precursor or a digest thereof using at least two different antibodies each of which can recognize a peptide comprising the partial amino acid sequence starting from amino acid residue 40 and ended at amino acid residue 75 in the amino acid sequence depicted in SEQ ID NO:1; and a method for the determination of a gastrin-releasing peptide precursor and/or a digest thereof using at least two different antibodies each of which can recognize a peptide comprising the partial amino acid sequence starting from amino acid residue 40 and ended at amino acid residue 79 in the amino acid sequence depicted in SEQ ID NO:1. The methods have such advantages that a detection sensitivity comparable to that in a conventional determination method can be achieved, that it is easy to handle a sample after the sample is collected, and that a highly reproducible measurements can be obtained.</p> |
申请公布号 |
EP1876445(A1) |
申请公布日期 |
2008.01.09 |
申请号 |
EP20060731744 |
申请日期 |
2006.04.13 |
申请人 |
ADVANCED LIFE SCIENCE INSTITUTE, INC. |
发明人 |
AOYAGI, KATSUMI |
分类号 |
G01N33/53;C07K16/26;C12N5/10;C12N15/02 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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