发明名称 |
METHOD TO IDENTIFY CD40-SENSITIVE CELLS USING GENE EXPRESSION |
摘要 |
A method of differentiating between first diffuse large cell B lymphoma (DLCBL) cells and second DLCBL cells, known to respond to CD40 mediated apoptosis, based on differences in expression of one or more genes or a profile of genes and a method to differentiate between CD40 sensitive and CD40 resistant DLCBL cells based on the differences in gene expression of recombination activating gene 1(RAG 1), pre-B lymphocyte gene 1 (VPREB 1), lymphocyte specific protein tyrosine kinase (LCK) and VAV 1 oncogene (VAV 1). |
申请公布号 |
WO2007082379(A3) |
申请公布日期 |
2007.12.27 |
申请号 |
WO2007CA00073 |
申请日期 |
2007.01.18 |
申请人 |
MCGILL UNIVERSITY;HOLLMANN, C. ANNETTE;SLADEK, ROBERT;OWENS, TREVOR |
发明人 |
HOLLMANN, C. ANNETTE;SLADEK, ROBERT;OWENS, TREVOR |
分类号 |
C12Q1/68;C07K14/705;C07K16/18;C07K16/40;C12N15/12;C12Q1/00;G01N33/53;G01N33/573;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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