| 摘要 |
After a primary ischemic injury, which predominantly results in necrosis, there is a secondary injury in the neighbouring tissue, due at least to some extent to apoptosis. This secondary damage is usually not evident until several days after the initial ischemic event. The present invention provides methods of preventing, treating and/or alleviating secondary ischemic damage in a mammalian organ or tissue, comprising a step of administering an effective amount of an NF-kappaB inhibitor to said organ or tissue. Compositions for this purpose are also disclosed.
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