发明名称 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
摘要 Provided herein are Aminopurine Compounds having the following structure: (I) wherein R1, R2 and and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
申请公布号 KR20070120940(A) 申请公布日期 2007.12.26
申请号 KR20077018501 申请日期 2006.01.13
申请人 SIGNAL PHARMACEUTICALS, LLC.;PHARMACOPEIA, INC. 发明人 ALBERS RONALD;AYALA LETICIA;CLAREEN STEVEN S.;DELGADO MEDEROS MARIA M.;HILGRAF ROBERT;HEDGE SAYEE;HUGHES KEVIN;KOIS ADAM;PLANTEVIN KRENITSKY VERONIQUE;MCCARRICK MEG;NADOLNY LISA;PALANKI MOORTHY;SAHASRABUDHE KIRAN;SAPIENZA JOHN;SATOH YOSHITAKA;SLOSS MARIAN;SUDBECK ELISE;WRIGHT JONATHAN;COLE ANDREW G.;HENDERSON IAN
分类号 C07D473/32;A61K31/52 主分类号 C07D473/32
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