| 摘要 |
A polymer modified porous substrate for solid phase extraction or chromatography, comprising a porous substrate and a polymeric monolith formed thereon, wherein the polymeric monolith comprises C<SUB>5-10 </SUB>monocyclic or bicyclic aryl or heteroaryl, optionally substituted with -L-Q<SUB>p</SUB>-R<SUB>q</SUB>; where q is 0-3, p is 0-5, Q is -NRC(O)-, -C(O)NR-, -OC(O)NR-, -OC(O)R-, -NRC(O)O-, -NRC(O)NR-, -NCO, -CHOHCHOH-, CH<SUB>2</SUB>OCHCH<SUB>2</SUB>O-, -(CH<SUB>2</SUB>CH<SUB>2</SUB>O)<SUB>s</SUB>-, -(CH<SUB>2</SUB>CH<SUB>2</SUB>CH<SUB>2</SUB>O)<SUB>s</SUB>-, -C(O)-, -C(O)O-, -CH<SUB>2</SUB>C(O)CH<SUB>2</SUB>-, -S-, -SS-, -CHOH-, -O-, -SO-, -SO<SUB>2</SUB>-, -SO<SUB>3</SUB>-, -OSO<SUB>3</SUB>, -SO<SUB>2</SUB>NR-, -NR<SUB>q</SUB>-, and -NR<SUB>q</SUB><SUP>+</SUP>-, -CN, -NC, -CHOCH-, -NHC(NH)NH-, -NO<SUB>2</SUB>, -NO, -OPO<SUB>3</SUB>-, -OH; and R is hydrogen, C<SUB>5-10 </SUB>monocyclic or bicyclic aryl or heteroaryl, C<SUB>1-12 </SUB>branched, unbranched, or cyclic hydrocarbyl; L is a bond or a C<SUB>1-12 </SUB>branched, unbranched, or cyclic hydrocarbyl. Methods of preparing and using the polymer modified porous substrates are disclosed.
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