发明名称 BUTORPHANOL-BASE INJECTION SOLUTION POSSESSING ANALGESIC EFFECT
摘要 FIELD: medicine, pharmacy. ^ SUBSTANCE: invention proposes an injection solution comprising the following components, wt.-%: butorphanol tartrate, 0.05-0.5; stabilizing agent, 1.6-5.4; chelating agent, 0.001-5.0, and water for injection, the balance. Invention provides decreasing concentration of active substance in preparing the equal pharmacological effect as compared with nalbuphine solution that allows reducing hazard effect of analgesic preparation on the body. The injection solution satisfies the quality index norm values for fitness period -3 years, not less. ^ EFFECT: improved and valuable medicinal and pharmaceutical properties of solution. ^ 6 cl, 9 ex
申请公布号 RU2312662(C1) 申请公布日期 2007.12.20
申请号 RU20060115636 申请日期 2006.05.10
申请人 OTKRYTOE AKTSIONERNOE OBSHCHESTVO "MOSKOVSKOE PROIZVODSTVENNOE KHIMIKO-FARMATSEVTICHESKOE OB"EDINENIE IM. N.A. SEMASHKO 发明人 KUCHUGURIN VLADIMIR ALEKSANDROVICH;BARILENKO IRINA IVANOVNA;BASKAKOVA VALENTINA GRIGOR'EVNA;DMITRENKO IRINA OLEGOVNA
分类号 A61K31/485;A61K9/08;A61P25/04 主分类号 A61K31/485
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