发明名称 |
METHOD OF PRODUCING 3-HYDROXYBUTYRALDEHYDE DERIVATIVE |
摘要 |
<p>The present invention relates to a method of producing a 3-hydroxybutyraldehyde derivative, particularly an optically active 3-hydroxybutyraldehyde derivative, which is useful as an intermediate of a pharmaceutical agent and the like. The method of the present invention is characterized by converting the 3-hydroxybutyrate derivative to an alcohol derivative by a reduction reaction followed by converting it to a desired aldehyde derivative by an oxidation reaction using a nitroxyl compound and a co-oxidant. In accordance with the present invention, a 3-hydroxybutyraldehyde derivative having high qualities (a low content of alcohol derivatives) can be produced by an easy and convenient method without resorting to a reaction under an extremely low temperature condition.</p> |
申请公布号 |
EP1862465(A1) |
申请公布日期 |
2007.12.05 |
申请号 |
EP20060729566 |
申请日期 |
2006.03.20 |
申请人 |
KANEKA CORPORATION |
发明人 |
IZUMIDA, MASASHI;MATSUMOTO, SHINGO |
分类号 |
C07F7/18;C07B53/00;C07C45/27;C07C47/19 |
主分类号 |
C07F7/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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