METHOD FOR PRODUCTION OF ACETIC ACID BACTERIUM-TYPE CERAMIDE

摘要

[PROBLEMS] To provide a method for efficient production of an acetic acid bacterium-type ceramide which is expected to have physiological activities such as an activity of making the skin beautiful, by increasing the content of ceramide in an acetic acid bacterium. [MEANS FOR SOLVING PROBLEMS] Provided is a method for increasing the content of an acetic acid bacterium-type ceramide, which can increase the content of acetic acid bacterium-type ceramide in an acetic acid bacterium to a level higher by 10 to 30 times than that in an untreated acetic acid bacterium. The method comprises maintaining an acetic acid bacterium after culture at pH 2.0 to 8.0 and a temperature ranging from 4 to 70°C for a period ranging from 3 hours to 7 days. The acetic acid bacterium used in the method is preferably Acetobacter malorum strain NCI1683 (FERM BP-10595) or Gluconacetobacter hansenii strain NCI1468 (FERM BP-10596).